Your starting weight, age, and presence of type 2 diabetes also influence response timelinesheavier patients and those with diabetes often see faster initial results
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Inhibition of dipeptidyl peptidase-4 reduces glycemia, sustains insulin levels, and reduces glucagon levels in type 2 diabetes
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Whether thats a dose issue, a formulation issue, the difficulty of controlling for diet and exercise, or a ceiling on what this mechanism can actually achieve in humans is still somewhat open