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Log2FC were shrunk using Bayesian estimator apeglm [79], and P -values associated with fold changes were adjusted for false discovery rate (FDR) using the Benjamini-Hochberg correction

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It has also been reported that LXR activation inhibits GSK3 phosphorylation, downregulates TCF-1 in CD4+ T cells, inhibits Tfh cells differentiation, and attenuates the GC response and antigen-specific IgG production (121)

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Race, ethnicity, age, sex, treatment type, functional status, rurality, and SVI were significantly associated with agreement

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Ultraviolet radiation increases generation of reactive oxygen and nitrogen species, which in turn enhance tyrosinase activity and thereby synthesis of melanin species within cells

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