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Important components of the cellular machinery controlling these processes are under transcriptional, translational, and posttranslational control by estrogen, and in vivo studies in humans have demonstrated sex-specific differences (49)

Activated macrophages are an adaptive element of the colonic epithelial progenitor niche necessary for regenerative responses to injury

Exenatide required twice-daily injections and represented a novel approach to treating type 2 diabetes by harnessing the body's natural glucose regulation mechanisms

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doi: 10.2337/db09-0278