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Schizandrol A promoted the activation of PI3K/Akt in acute myocardial ischemia mice and H9c2 cells treated with oxygenglucose deprivation, downregulated the expression of NOX2, as well as significantly reduced myocardial infarction area and improved biochemical indicators and cardiac pathological changes, thus exerting cardiac protective effects (50)

This results in higher levels of intracellular glutathione

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All patients were required to engage in low-level physical activity consisting of 2 hours slow walking per day