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Mainly expressed in the ileum and colon, GLP-1 is known as the most powerful incretin in humans and lowers postprandial blood glucose via augmentation of glucose-dependent insulin release from pancreatic -cells, inhibition of glucagon secretion from pancreatic -cells, and delay of GE

The safer choice depends on contraindications, other medications, diabetes treatment, gastrointestinal history, pregnancy considerations, and individual tolerance

Yerba mate may prevent diabetes according to a crossover, randomized, controlled study in humans

Consult your healthcare provider for personalized recommendations