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Am J Physiol-Heart Circulat Physiol 297(1):H13-20 De Vivo DC, Nordli C, Dimauro S (2002) Mitochondrial dysfunction, epilepsy, and antiepileptic drugs

Another 12-year prospective population-based study demonstrated that the braingut pathway is bidirectional: elevated baseline anxiety levels predicted new-onset functional gastrointestinal disorders 12 years later, while individuals with functional gastrointestinal disorders at baseline exhibited significantly elevated anxiety and depression levels at follow-up (Koloski et al., 2012)

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Potential Neuroprotection GLP-1 receptors are present in the brain, and GLP-1 acts as a neurotransmitter

The MHRA regulates the approval of new medicines in Great Britain following the UK's departure from the European Union, whilst the EMA retains responsibility for authorisation across EU member states