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To check the validity of these selected SNPs as genetic instruments, we calculated the F-statistic, using a well-established formula [21]

Formalin-fixed paraffin sections were also subjected to terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) method for evaluation of cell death as previously described [39]

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Figure 1: Mechanism of detection used in the GXP4 Assay Kit