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GLP-1 mimics a natural hormone in your body that helps: Regulate blood sugar levels Reduce appetite and cravings Slow stomach emptying Support consistent calorie reduction By helping you feel fuller longer, GLP-1 supports gradual, sustainable weight loss without extreme dieting or synthetic quick fixes

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[email protected] These authors have contributed equally to this work

The activity of MC4R is strictly regulated by its endogenous ligands: -melanocyte-stimulating hormone (-MSH) binds to MC4R and transmits anorexigenic and energy-expenditure signals, whereas agouti-related protein (AgRP) exerts an antagonistic effect by binding to the receptor, competitively inhibiting -MSH action and promoting appetite