This type of indirect comparison has significant limitations: The company references the comparison trial as including "a daily 500-calorie deficit, 150 minutes of weekly exercise, and in-person counseling every four weeks." These are substantial lifestyle interventions that may not be replicated in all real-world telehealth settings, making the comparison complex to interpret
Conversely, treatment with GHK-Cu led to a significant reduction in this score (Figures 1D,E)
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GLP-1 agonists for obesity-a new recipe for success
8 Ospedale Santo Stefano, Neurology Department, Prato, Italy
