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This distinction affects how the compound is absorbed, metabolized, and utilized in the body

What is missing There is no published human pharmacokinetic study of subcutaneous AOD-9604, no published human topical or intranasal exposure data, no Phase 3 efficacy trial, no long-term safety data beyond 24 weeks, and no published human cartilage or joint outcome data

via Healthline

Incorporating B12 into Your Wellness Routine Regardless of which option you choose, integrating B12 into your daily health regimen can result in numerous overall health benefits

If you are concerned about maintaining optimal health and ensuring that your body gets the nutrients it needs, B12 shot are often the superior choice