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PDH catalyzes the formation of acetyl coenzyme A, a crucial step in energy production, and, through acetyl-CoA, serves as a precursor for acetylcholine (ACh), which is vital for nerve signal transmission and muscle function since ACh acts on the communication between neurons and in the neuromuscular junction, as well as for myelin production in nerve cells (40)

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Understanding where it fits helps clarify why the reagent properties matter

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