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Efficacy of LAG-1 degradation was assessed by determining the relative mRNA abundance of GLP-1/LAG-1 transcriptional targets, lst-1 & sygl-1 , by qRT-PCR, following auxin treatment

Moreover, current studies with long-term exposure to GIP receptor antagonism have only been conducted during co-stimulation of the GLP-1 receptor which induce a drug class-specific adverse effect profile, including nausea and vomiting (84, 116)

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