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Dihydroartemisinin can induce A549 cell cycle arrest by reducing the expression levels of key G0/G1 regulators, including cyclin dependent kinase 2 (CDK2), cyclin dependent kinase 4 (CDK4), and cyclin E1, and the mTOR/HIF-1 signaling is one of the potential key pathways involved (Li Y

However, some patients report different levels of GI sensitivity between the two

This indicates that DA-CH5 has a greater comprehensive advantage and more optimal target sites, making it more likely to be used clinically in the future compared to DA-JC4 and DA-JC1

GLP-1RAs, which achieved great success in 2023 and draws peoples attention back to obesity treatments and GLP-1 therapies worldwide, was chosen as the breakthrough of year 2023 by Science [2]

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