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The study population was 36.5% male, with a mean (SD) age of 76 (5) years, and 68.2% were high school graduates

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Overall, simultaneous promotion of macrophage phagocytosis of MSU crystals and inhibition of MSU crystal-induced generation of inflammation may reduce the inflammatory response more rapidly.Therefore, inhibiting MSU crystal phagocytosis or reducing the expression of inflammatory factors post-phagocytosis may present an efficient therapeutic approach during MSU production