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Kresladi, a lentiviral vector-based gene therapy to treat severe leukocyte adhesion deficiency-I (LAD-I), has already faced delays from the agency as it was initially supposed to find out its fate in March 2024

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A: Minimum 98% purity confirmed by HPLC, with LC-MS molecular identity confirmation (C78H123N23O23S2, ~1,817 Da)

Indeed, the percentage of dead cells (necrotic+apoptotic cells according to the DNA content analysis) in DEM and BSO treated cells remained low during the first 3 days in culture

Since Ozempic is often prescribed for diabetes or prediabetes, adding compounds that influence glucose metabolism requires monitoring