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Wegovy (semaglutide) acts only on the GLP-1 receptor , which primarily reduces appetite and slows gastric emptying

Acute Kidney Injury : Due to the potential for volume depletion from gastrointestinal side effects, kidney function should be monitored in patients with renal impairment

Yes, anything that causes rapid weight loss can cause changes to your facial appearance

These data suggest that EGFR is necessary for a normal insulin response, and that exendin-4 amplifies the insulin response through -cell EGFR

Semaglutide works through a single, well-studied mechanism (GLP-1 receptor activation) that produces durable weight loss and improves metabolic health without cardiovascular overstimulation