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Mol Metab 6:245255 Mendoza MC, Er EE, Blenis J (2011) The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

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Potential side effects include: Dry mouth Trouble sleeping Feeling jittery Anxiety Increased heart rate Elevated blood pressure Constipation Fortunately, these effects are often dose-dependent and improve with dose adjustments or timing changes