Editor's note: The original article, published in Undark and co-published with STAT , draws on a seven-month investigation by journalist Sara Talpos
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More comprehensive metal-binding studies of NiCo riboswithces from Eba and Listeria monocytogenes reveal a metal binding stoichiometry of three in solution, with metal site 4 (Figure 22D) playing no regulatory role, and likely an artifact of the high Co II concentration used in the crystallographic experiments