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Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food

Kannt A, Pfenninger A, Teichert L, Tnjes A, Dietrich A, Schn MR, Klting N, Blher M. Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance. Diabetologia. 2015 Apr;58(4):799-808. doi: 10.1007/s00125-014-3490-7. Epub 2015 Jan 18. PMID: 25596852; PMCID: PMC4351435

The Firmicutes phylum contains the majority of the bacteria that produce TMA, including some Actinobacteria and Proteobacteria as well as Clostridium cluster XIVa and Eubacterium strains (184)

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doi: 10.1007/s11102-017-0849-z 22 BlumWFAlbertsson-WiklandKRosbergSRankeMB