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& Zanotti, S

44 The 52-week data from 966 patients with MASH and F1B, F2, or F3 fibrosis in the MAESTRO-NASH trial revealed significant effects of resmetirom on MASH resolution, fibrosis improvement, and LDL cholesterol reduction (NCT03900429), 77 forming the basis for potential FDA approval of resmetirom for MASH treatment

38, June 2023, pp

Underlying conditions that can impair treatment response include hypothyroidism, polycystic ovary syndrome (PCOS), Cushing's syndrome, obstructive sleep apnea, and psychiatric conditions like binge eating disorder

Systematic proteomic analysis of protein methylation in prokaryotes and eukaryotes revealed distinct substrate specificity