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In individuals with obesity without T2DM, SURMOUNT- 1 evaluated the safety and effectiveness of tirzepatide 5, 10, and 15 mg once weekly in comparison to a placebo when paired with a 500 kcal/day deficit diet and recommendations for 150 min of weekly exercise [118]

In clinical trials, patients achieved weight loss of approximately 15-20% from baseline after 72 weeks, with results varying by dose and whether patients had diabetes

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Gut Health Gut microbes react quickly to diet, drugs, and when you eat