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Non-responders after gastric bypass surgery for morbid obesity: peptide hormones and glucose homeostasis

Through inhibition of key targets, such as TGF- and P4HA1, GLP-1RAs exert antifibrotic and immunomodulatory effects, demonstrating protective potential in multiple organs, including the heart, kidneys, liver and lungs (160)

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A linear mixed effects model was fit to each data set, with age as the fixed effect and animal as the random effect