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In AD lesions, Th2 cytokines such as IL-4 and IL-13 are chronically secreted, and these cytokines commonly activate the transcription factor signal transducer and activator of transcription 6 (STAT6) (Heckert et al

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In 2004, he moved his laboratory to the Penn State University College of Medicine where he is a member of department of public health sciences and the Penn State Hershey Cancer Institute

While these radicals are essential for pathogen clearance, excessive or chronic inflammation can lead to tissue damage due to the persistent high levels of free radicals [58]