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The tripeptide binds copper with high affinity (log stability constant of 16.44) and delivers it to tissue sites where copper-dependent enzymes (lysyl oxidase, superoxide dismutase, cytochrome c oxidase) drive collagen crosslinking, antioxidant defense, and mitochondrial respiration [1][2]

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This effect occurs without changes in fusion protein expression or mitochondrial number and is attributed to enhanced SIRT3 activity, which promotes SOD2 deacetylation and indirectly inhibits kinases that phosphorylate DRP1 at Ser616 68

In addition he has also received a Pushcart Prize and the Hispanic Heritage Award for Literature

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