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Efficacy and safety of a biased GLP-1 receptor agonist ecnoglutide in adults with overweight or obesity: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

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RNR-dependent nucleotide synthesis may therefore compete with GPX4-dependent lipid hydroperoxide reduction for use of the same co-substrate, namely GSH

Post hoc analyses for the primary endpoint included a subgroup analysis by sex and a sensitivity analysis exploring effects of study sites

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