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It eliminates confounding variables and allows the true effects of the compound to be observed

Modulating PC metabolism may restore synaptic integrity and mitigate neurodegenerative processes in AD

Lancet 397 , 20602069 (2021)

Among different PEG densities (3%, 7%, 10%, 15%), 10% PEG-Lips achieved the highest blood drug concentration (using oral FITC-dextran 4,000 as an indicator)

For any synthetic AT developed, it is important to know which biomolecule the agent is designed to protect, by which mechanism (scavenging RS, preventing RS formation, increasing endogenous defense mechanisms, and/or supporting oxidative damage repair), whether it can generate RS, and if there are any adverse effects associated with RS suppression