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At 26 weeks, cagrilintide 0.3 mg, 0.6 mg, 1.2 mg, 2.4 mg, and 4.5 mg resulted in 6.1%, 6.8%, 8.4%, 9.5%, and 10.6% weight loss, respectively, compared to 8.4% with liraglutide 3 mg/day and 2.8% with placebo [39]

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Immunologically, the NOH 2 S axis modulates dendritic cell activation and suppresses MDSC expansion, thereby restoring antitumor immunity

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