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the medication physically slows stomach emptying, making it difficult to overeat even if you wanted to

As of the time of writing, retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) and it remains under clinical investigation

Now, let's say your research protocol calls for a 20mg dose

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Those who were then randomly assigned to keep taking the drug for 48 more weeks lost another 16 pounds, while those who were switched to a placebo for those 48 weeks gained 13 pounds