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Mice were treated with pharmacological agents by either intraperitoneal (i.p.) injection or inclusion in the drinking water

This study demonstrates that delivery of oxidized Coenzyme Q 10 (ubidecarenone) to increase mitochondrial Q-pool is associated with an increase in ROS generation, effectuating anti-cancer effects in a pancreatic cancer model

102,103 Digestion of hesperidin produces a compound called hesperetin along with other metabolites

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The emergence of loss of efficacy during antidepressant drug treatment for major depressive disorder: an integrative review of evidence, mechanisms, and clinical implications