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however, as with all prescribed and over the counter preparations, we still need to remain vigilant. The research comes just weeks after the Therapeutic Goods Administration (TGA) issued firm advice not to initiate semaglutide prescriptions without a compelling clinical reason

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Its worth being clear-eyed about the studys limits: it was a single-center, retrospective chart review, not a randomized trial, and nearly a third of patients discontinued the medication, most often due to gastrointestinal side effects

When combined with GLP-1, it appears to enhance glucose control and may improve tolerability, allowing higher therapeutic doses with fewer gastrointestinal side effects in many people