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Unlike broad-spectrum anabolic compounds, peptides target specific receptor pathways with high selectivity, making it possible to stimulate particular physiological processes growth hormone release, tissue repair, muscle protein synthesis, satellite cell activation without the systemic hormonal disruption of anabolic steroids or exogenous growth hormone

While gene therapy is available for a small subset of patients with specific mutations, developing a therapeutic that broadly targets the cellular stresses that lead to cell death could address a major unmet need

Similarly, reduced physical activity due to illness, injury, or lifestyle changes decreases energy expenditure

Michels N, et al

During periods of calorie restriction, maintaining lean muscle is critical because muscle tissue plays a central role in metabolism