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However, diagnosing Wilson disease as the cause of acute liver failure can be challenging because elevated serum and urine copper levels are not specific to Wilson disease and can be seen in patients with acute liver failure from any cause

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Crucially, by generating patient-specific data prior to clinical enrollment, these systems can inform trial design, identify likely responders, and support patient stratification, thereby complementing and reducing the risks associated with clinical trials

A deep investigation was carried out to evaluate the reliability of the model, analyzing cell morphology, peripheral blood mononuclear cells (PBMC) recruitment, cytokine production, as well as the transcriptomic analysis, highlighting the relevance of the chip

Stockmann-juvalaH.MikkolaJ.NaaralaJ.LoikkanenJ.ElovaaraE.SavolainenK.FuminisinB.1induced toxicity and oxidative damage in U-118MG glioblastoma cells