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The peptide sequence (glycine-histidine-lysine) chelates copper ions in a way that allows controlled cellular uptake without the oxidative damage that free copper can cause

Of interest, patients with metabolic diseases, such as obesity and type 2 diabetes 35 have been reported to have a reduction of bacterial riboflavin synthesis genes in their gut microbiome, suggesting that microbially-produced riboflavin could play a role in these diseases, although the causal association remains to be established

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