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Therefore, mutations in the PLPBP gene disrupt this process, causing PLP to react with other substrates and impacting the metabolism of important amine or amino acid neurotransmitters in the brain, consequently leading to the development of epilepsy

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When you take oral B12 supplements, your digestive system must first break down the pill, then rely on intrinsic factora protein produced in your stomachto absorb the vitamin

If you take both metformin and tirzepatide, your risk of B12 deficiency is compounded (no pun intended)

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