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As a result, some patients notice increased hollowness, sagging skin, more visible fine lines and wrinkles, or a generally more tired appearance

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Patients must also manage any nausea or vomiting and meet their nutrition goals, including taking daily vitamin and nutrient supplements and eating enough protein

It is important to note that retatrutide has not received marketing authorisation from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA) , and no UK Summary of Product Characteristics (SmPC) or European Public Assessment Report (EPAR) exists for this medicine

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