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When a very large doses of paracetamol are taken, the glucuroconjugation capacity is saturated, more NABQI is formed, hepatic glutathione is depleted and NABQI binds covalently to proteins in liver cells (and renal tubules) causing necrosis

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Consequently, while triple agonists represent an important advancement in obesity pharmacotherapy, their safety, tolerability, and long-term developmental effects in adolescents remain unknown

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which provides 2000 IU of SOD