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In line with evidence accrued in patients with T2D, incretin-based therapies produced a favorable effect on traditional cardiovascular risk factors, such as lipids and blood pressure, and even reduced the risk of major cardiovascular events and heart failure-related events in individuals with obesity, as recently demonstrated for the first time in the SELECT trial with semaglutide 2.4 mg once-weekly
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Some people might lose more, and some might lose a bit less
A recent 27 real-world study reported weight loss outcomes of semaglutide use in patients with or without a previous history of bariatric surgery
However, semaglutide also has extensive safety data from its use in type 2 diabetes (as Ozempic) since 2018
Metformin is the first-line treatment for type 2 diabetes because its a safe, affordable, and effective medication
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