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The methioninehomocysteine cycle, in turn, obtains the methyl group from the folate cycle and supplies precursors for the production of glutathione and taurine via the transsulfuration pathway (Supplementary Fig
For NS5B region, a fragment (382 nt) was amplified by RT-PCR touch Down followed by semi-nested PCR using the same primers as previously reported by Laperche et al