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Pandit, S., Biswas, S., Jana, U., De, R

Reference: Willard FS et al

Key Study Findings Incidence rates for pancreatitis (aHR 9.1, 95% CI 1.25-66), bowel obstruction (aHR 4.2, 95% CI 1.02-17.4), and gastroparesis (aHR 3.7, 95% CI 1.2-11.9) were significantly higher among users of GLP-1 agonists compared to buproprion-naltrexone users

Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis

In the SURMOUNT-1 obesity trial, participants achieved weight loss averaging up to approximately 21% of baseline body weight at 72 weeks with the 15 mg dose

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