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Thus, any treatment capable of augmenting glucose metabolism in -cells may result in clinical benefit from improvement in insulin secretion and overall glucose homeostasis

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These studies suggest that deficiencies in GH and IGF-I contribute to a functional decline in senescent rats, whereas augmentation of GH or IGF-I improves cognitive function, increases glucose utilization throughout the brain, increases cortical vascularity, and ameliorates age-related decline in hippocampal neurogenesis

Gray literature sources report doses in the range of 5-10mg per week