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M., Astrup, A., & Hjorth, M

Tirzepatide is a dual GIP/GLP-1 agonist with ~5-day half-life vs semaglutide's ~7-day half-life

While the less frequent subcutaneous dosing (once-weekly vs liraglutide's once-daily subcutaneous injection) or the daily oral intake of tablets may seem appealing, there is a lack of RCT data regarding the effects of these compounds on BAD symptoms

"The effects of L-carnitine supplementation on glycemic control: a systematic review and meta-analysis of randomized controlled trials." National Library of Medicine

Injecting MTX to carnitine-depleted rats caused 98% and 67% reduction in serum total carnitine and 98% and 65% reduction in serum free carnitine compared to control and MD groups, respectively