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VSMC phenotypic switching is characterized by transformation from a quiescent contractile to an activated synthetic phenotype, promoting proliferation and leading to the formation of the neointima, the pathological vascular compartment critical for the development of atherosclerosis

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Their results also suggested that NK1 and NK3 receptors may induce glandular effects by different mechanisms NK3 receptors are likely inducing activation of parasympathetic nerves, while NK1 may have direct effect on the glands [80]

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Cinnamon does not directly increase GLP-1 production, but research suggests it may enhance insulin sensitivity and glucose control through mechanisms that complement GLP-1 signaling