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Finally, avoid using alternative medicine as a substitute for conventional treatment, to treat yourself or to postpone a visit with your care provider

Compared with other CVOTs involving GLP-1RA, participants in the AMPLITUDE-O trial had the longest duration of diabetes (15 years), lowest mean eGFR (72 ml/min/1.73 m 2 ) with a higher percentage (32%) of people with renal disease (eGFR 2560 mL/min), highest glycosilated hemoglobin (8.9%), and highest percentage of insulin use (62%) or sodiumglucose transporter-2 inhibitors (SGLT-2i) (15%) at baseline, thus identifying a more fragile population

GIP for enhanced insulin secretion and lipid metabolism

For clinicians, the ask is more immediate: Pause before treating BMI as sufficient justification for a prescription

None of this infrastructure exists for Melanotan II