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This magnitude of body weight reduction had not been reported to date in any other phase 2 or 3 trials testing weekly GLP-1RA or GLP-1R/GIPR dual agonists in patients living with T2DM, potentially due to the additional agonism of the glucagon receptor (Grunberger et al
Clinical trial data shows that participants in the STEP program saw the majority of their total weight loss occur in this window
The standard is met through the prescribers clinical attestation, and the programme does not require documentation of a specific diet or exercise regimen beyond what the prescriber certifies
According to the study, funded by Eli Lilly, people taking Zepbound lost 20.2% of their body weight after 72 weeks, while people taking semaglutide drugs lost 13.7%
However, prescription Egrifta requires a valid prescription
