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Li H, Sun Z, Jiang S, Lai X, Bckler A, Huang H, et al

Biotechnol Appl Biochem (2023) 70(1):17583

Unlike in adults, children and adolescents need energy and sufficient calories not only for physical activity, but for growth and development." The balance of energy intake (diet) and energy expenditure (such as physical play and exercise) influences a childs growth and health across their lifespan, and any change in the balance of these two factors can adversely impact health much later in life

The optimal approach may depend on individual health goals and the type of therapy being used

Gradient of risk and associations with cardiovascular efficacy of ertugliflozin by measures of kidney function: observations from VERTIS CV