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To fully unlock the translational potential of PDCOs, it is essential to overcome current technological and standardization challenges that limit their reproducibility, scalability, and predictive accuracy

When tirzepatide is covered, prior authorization may be required

(3) The dipeptide Boc-His (Trt) -Aib-OH is adopted, so that racemization of amino acid can be better avoided compared with dipeptide protected by Boc on Fmoc or His, the stability is better, the reaction monitoring is facilitated, and the condition that other groups of a side chain need to be protected in advance is avoided

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