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How to Talk to Your Doctor About GLP-1 Weight Loss Drugs Chronic Diseases That GLP-1s Are FDA-Approved to Treat GLP-1s for Heart Disease In March 2024, the FDA approved the GLP-1 drug Wegovy (semaglutide) to treat heart disease in people who are overweight or who have obesity the first approval for a GLP-1 medication outside of diabetes or weight loss