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Diseases associated with mutation of transcription co-activator families Considering the compendium of previously stated facts on transcriptional co-activators, it is now quite evident that co-activators are indispensable for establishing homeostasis during gene expression
Research on MOTS-c in ovariectomized mice (a model for postmenopausal metabolic dysfunction) showed reduced fat accumulation in white adipose tissue, increased brown fat activation, and improved insulin sensitivity after just 5 weeks of treatment
Amongst the hydrolysis products, isothiocyanates (e.g., SFN) were reported to possess protective and anticarcinogenic effects when consumed in a cruciferous-rich diet ( SFN has been reported to have therapeutic and medicinal effects in the treatment of cancer, autism, Helicobacter pylori , asthma, and liver disease ( To date, the use of SFN for the treatment and prevention of different types of cancers is supported and widely investigated in preclinical, clinical, and epidemiological studies ( 2 Methods 2.1 Protocol and registration The protocol of this systematic review was registered in the PROSPERO database (ID: CRD42022323788 )
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Synbiotics containing sea buckthorn polysaccharides ameliorate DSS-induced colitis in mice via regulating Th17/Treg homeostasis through intestinal microbiota and their production of BA metabolites and SCFAs
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