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They are precise, targeted, and degrade naturally in the body

UA, as scavenger of oxygen radical, contributes to approximate 60% of plasma antioxidant activity and maintains the stability of blood pressure and antioxidant stress (Nieto et al., 2000

Endogenous MOTS-C levels rise during exercise and return to baseline within about four hours, so the timing logic tracks

Studies have shown that certain bacterial genera such as Bacteroides, Akkermansia, Faecalibacterium, Roseburia, and Bifidobacterium are negatively associated with T2DM, while others like Blautia, Fusobacterium, and Ruminococcus are positively associated with T2DM [156]

Osthole regulates microRNA-22-3p-mediated lipid metabolic reprogramming, reduces serum total cholesterol and triglyceride/high-density lipoprotein cholesterol ratio, inhibits fatty acid transporters such as CD36 and fatty acid synthase (FAS), decreases fatty acid uptake, synthesis, and oxidation, and alleviates pulmonary vascular remodeling in PAH (Niu et al., 2022)