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Studies indicate that KD can be used in both short and long terms (231)

As long as youre not experiencing any serious side effects and the drug is effective, you can remain on it for quite some time safely

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However, once these patents expire, generic manufacturers could enter the market relatively quickly, as the synthesis of a small molecule like orforglipron does not require the specialized SPPS facilities and expertise needed for generic peptide production

10 Thus, using Semaglutide in older patients with T2DM may exacerbate the development of sarcopenia due to negative energy balance